Showing posts with label d. Show all posts
Showing posts with label d. Show all posts

Vitamin D Levels Dramatically Lower Cardiovascular Risk

Saturday, April 19, 2014

It has been widely reported that US deaths from cardiovascular disease has recently overtaken cancer as the Number 1 killer of people of all ages. The news media has been quick to blast these headlines everywhere. And the pharmaceutical companies are also quick to tell all who will listen that their latest and greatest drug will lower total cholesterol and LDL-C, thus reducing heart attack risk. If only it were that simple... and true!

The problem is that many recent reports have proven that cholesterol (and even the much maligned LDL-C) are really not your enemy. In fact, they are critical blood components which provide our bodies with the ability to synthesize new cells, form hormones and a large variety of other critical cellular functions. When these levels are artificially reduced, essential molecular duties are limited, and the homeostasis in the body is disrupted. Pharmaceutical makers (and your doctor) love the statin drugs because they predictably lower blood markers in a dose dependent manner. Take this amount of drug, and you will reduce your cholesterol by this amount. In fact, it has been demonstrated that statins help only 1 in 100 people partially avoid a second heart attack, likely through the statins ability to modestly reduce systemic inflammation. All nice and pretty... and thus a multi-billion dollar category of drugs is born.

The latest research is clearly demonstrating that arterial plaque is not directly formed by cholesterol being stuffed into the walls of our arteries, but by a very complex process which is triggered through our immune system through inflammation. Components of our white blood cells known as macrophages are actually the culprit, as they lose their protein coating in a response to arterial inflammation. It are these white blood cell macrophages which create the foamy plagues which plug up the micro openings in the arteries which occur due to excessive abuse in our body. This abuse is caused by a large number of factors, but the short list includes poor dietary factors (ined carbs, fast foods, fried foods) and high blood pressure. From the perspective of our bodies, it is attempting to save our lives, as these micro cracks in the arterial walls could easily lead our bleeding-out. It is ironic that the mechanism used to help us survive is often the same one which leads to our premature demise. Vitamin C is also critical in avoiding the micro cracks, as it assists the body to create collagen which can help to repair the tiny tears in the vessel walls. More about the role of Vitamin C in a future post.

Now that we understand that the local pharmacy does not have the answer to help us avoid cardiovascular disease, how can we eliminate this risk? The simple answer is through eating a proper diet which is low in ined carbs, sugar and especially high-fructose corn syrup and trans-fats and cooked animal fats, maintaining a healthy body weight and correcting the blood level of Vitamin D. OK, the first two we have all heard about, but the Vitamin D component just doesnt seem to get that much media attention. The very latest studies have confirmed that maintaining an optimal Vitamin D blood level of 50 - 70 ng/ml will reduce the chance of developing heart disease by 50%! As this is the primary killer of people in the US and other western countries, wouldnt that merit a major headline? Hard to believe that you probably will never hear of this information. But yet Vitamin D has been demonstrated to help blood vessels to dilate, reduce levels of dangerous triglycerides and reduce inflammatory factors in the blood. By ensuring a proper level of Vitamin D in the blood through either sun exposure (only if less than 50 years old) or supplementation (remember, in a gelcap form), we can cut in half the number of people subjected to heart disease.

If only there were millions to be made by pharmaceutical entities through the sale of Vitamin D, we could save literally millions of lives each year. Good thing you now know this vital information and can begin taking steps to protect your own health.

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Importance of Vitamin D for Smokers

Friday, April 11, 2014

Importance of Vitamin D for Smokers | In addition to bone health, recent research reveals about the benefits of vitamin D which is great for health, including preventing cancer. In a recent study revealed that: the benefits of vitamin D in protecting the lungs, especially for those who smoke.

In his study, Nancy E. Lange, MD, MPH, of the Channing Laboratory, Brigham and Womens Hospital studied 626 Caucasian men over a period of 20 years. The study assessed three time periods are completely different between 1984 and 2003. Pulmonary function of each participant was measured using a spirometer.


"Our results indicate that vitamin D may modify the damaging effects of smoking on lung function. This effect might be due to vitamin D has anti-inflammatory properties and anti-oxidants,"
said Lange.

This study has several limitations, including the observational information. Vitamin D levels are also likely to vary from time to time. Another limitation of this study involved only older men.

Alexander C. White MS, MD, chairman of the committee of the American Thoracic Society Tobacco Action, said: enough or not vitamin D levels in a person, should not overshadow the health risks and dangers associated with smoking. Those who smoke should be aware of the consequences of health problems that may be obtained.

The study is published in the American Journal of Respiratory and Critical Care Medicine.
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Vitamin D Supplements Wont Help Prevent Disease Review

Thursday, April 10, 2014


Low levels of vitamin D have been implicated as a potential cause of diseases ranging from cancer to diabetes. Now an extensive review suggests its really the other way around: Low levels of the "sunshine vitamin" are more likely a consequence -- not a cause -- of illness.

In their review of almost 500 studies, the researchers found conflicting results. Observational studies, which looked back at what people ate or the kinds of supplements they took, showed a link between higher vitamin D levels in the body and better health.

But, in studies where vitamin D was given as an intervention (treatment) to help prevent a particular ailment, it had no effect. The one exception was a decreased death risk in older adults, particularly older women, who were given vitamin D supplements.

"The discrepancy between observational and intervention studies suggests that low [vitamin D] is a marker of ill health," wrote review authors led by Philippe Autier, at the International Prevention Research Institute, in Lyon, France.

Vitamin D is known to play a key role in bone health. Low levels of vitamin D have been found in a number of conditions, including heart disease, autoimmune diseases, diabetes, cancer and Parkinsons disease. These findings may explain why so many Americans are currently taking vitamin D supplements.

Its nicknamed the sunshine vitamin because the body produces vitamin D when exposed to the sun (if someone isnt wearing sunscreen). Its also found in some foods, such as egg yolks and fatty fish, and in foods that have been fortified with vitamin D, such as milk.

The current review, published online Dec. 6 in The Lancet Diabetes & Endocrinology, looked at 290 observational studies. In these studies, blood samples to measure vitamin D levels were taken many years before the outcome of the study occurred. The review also included results of 172 randomized clinical trials of vitamin D. In randomized trials, some people receive a therapy while others do not.

The observational studies showed a potential benefit from vitamin D. For example, vitamin D was associated with a 58 percent reduced risk of cardiovascular events, a 38 percent decreased risk of diabetes and a 34 percent decreased risk of colon cancer in these studies.

But, when the researchers looked to the randomized clinical trials that used vitamin D as a treatment, they failed to find any effect on disease occurrence or severity from raising vitamin D levels.

However, vitamin D did reduce the risk of dying from any cause in older people taking 800 international units a day, according to the review.

Dr. Shaun Jayakar, an internal medicine and geriatric specialist from St. John Hospital and Medical Center in Detroit, said the findings in elderly people "are likely due to a reduction in falls and fractures. Supplementing with vitamin D would lead to stronger bones, which would reduce falls and factures."

Because the majority of interventional trials failed to find any benefit from vitamin D, the reviews authors conclude that low vitamin D levels dont lead to ill health, rather theyre caused by ill health.

They theorize that inflammation that occurs in many illnesses may be what depletes vitamin D levels.

Dr. Robert Graham, an internist from Lenox Hill Hospital in New York City, said, "This comprehensive review did a really good job at trying to tease out the effects of different study designs, and the findings will be controversial."

He said there are currently five, large ongoing interventional trials that will help to better define vitamin Ds role in disease. However, the results of those studies wont be available for a number of years. Until then, he recommended, "Try to achieve homeostasis [equilibrium]. You dont want to get to a low level of vitamin D."

The Institute of Medicine recommends 600 international units of vitamin D for adults, and 800 international units for people over 70.

Both Graham and Jayakar agreed that those are reasonable supplement levels. Jayakar said that for most people, vitamin D supplements are harmless, but added that "its a pocketbook issue. Almost 50 percent of the population is taking vitamin D supplements. Thats a lot of money for something that likely has no benefit," he said.

Jayakar added that this reviews findings suggest that low vitamin D levels could be used as a marker -- a sign -- of disease in younger people. "If someone isnt feeling well and they have low vitamin D, maybe we should use that to start searching to see if something else is going wrong," he said.
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